Rome2Rio

How to get fromWorcester to St. Louisby bus, plane, train (Amtrak), bus (Greyhound), or car

Find Transport to St. Louis

See all options

There are 10 ways to get from Worcester to St. Louis by bus, plane, train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly

    best
    1. Take the bus from Worcester to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    6h 30m
    $370–878

  2. Fly from Worcester Regional Airport

    cheapest
    1. Fly from Worcester Regional Airport (ORH) to Lambert–St. Louis International Airport (STL)plane plane ORH - STL
    9h 23m
    $145–705

  3. Train (Amtrak)

    1. Take the train from Worcester Union Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    26h 52m
    $407–825

  4. Bus

    1. Take the bus from Worcester Union Station to Newark Penn Stationbus bus Greyhound US0235 / ...
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus Greyhound US0421
    27h 10m
    $185–366

  5. Drive 1,112.7 mi

    1. Drive from Worcester to St. Louiscar car 1,112.7 mi
    19h 45m
    $204–294

  6. Bus to Bradley International Airport, fly

    1. Take the bus from Worcester to Hartfordbus bus
    2. Fly from Bradley International Airport (BDL) to Lambert–St. Louis International Airport (STL)plane plane BDL - STL
    8h 6m
    $148–691

  7. Bus to Theodore Francis Green State Airport, fly

    1. Take the bus from Worcester Union Station to Providencebus bus
    2. Fly from Theodore Francis Green State Airport (PVD) to Lambert–St. Louis International Airport (STL)plane plane PVD - STL
    8h 30m
    $147–679

  8. Bus to Laguardia Airport, fly

    1. Take the bus from Worcester to New Yorkbus bus
    2. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    8h 27m
    $204–899

  9. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Worcester Union Station to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    8h 24m
    $426–894

  10. Bus via New York

    1. Take the bus from Worcester to New Yorkbus bus Ppb 5725 / ...
    2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    27h 35m
    $198–413

Worcester to St. Louis by train (Amtrak)

Calendar7Weekly Trains
Duration26h 52mAverage Duration
Ticket$407Cheapest Price
See schedules

Questions & Answers

Map of how to get from Worcester to St. Louis.ExpandLaunch map view
  • Distance: 1,102.7 mi
  • Duration: 6h 30m

What companies run services between Worcester, MA, USA and St. Louis, MO, USA?

You can take a train from Worcester Union Station to St. Louis via Chicago Union Station in around 26h 52m. Alternatively, you can take a bus from Worcester Union Station to St Louis Bus Station via Newark Penn Station in around 27h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers