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How to get fromWytheville to Chicagoby bus, plane, train, car, shuttle, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Wytheville to Chicago by bus, plane, train, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Yeager Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Wytheville to Charleston, WVbus bus
    2. Fly from Yeager Airport (CRW) to Chicago O'Hare International Airport (ORD)plane plane CRW - ORD
    6h 24m
    $92–369

  2. Drive to Greenbrier Valley Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Wytheville to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane plane LWB - ORD
    4h 54m
    $65–311

  3. Bus

    1. Take the bus from Wytheville to Columbusbus bus Bsb 33
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Chicagobus bus Columbus / ...
    16h 25m
    $83–187

  4. Bus, train

    1. Take the bus from Wytheville to Ashlandbus bus Charlotte
    2. Take the train from Ashland Amtrak Station to Chicago Union Stationtrain train Cardinal
    18h 15m
    $153–358

  5. Drive  605.8 mi

    1. Drive from Wytheville to Chicagocar car 605.8 mi
    10h 38m
    $111–160

  6. Bus to Roanoke Regional Airport-Woodrum Field, fly to Chicago O'Hare International Airport

    1. Take the bus from Wytheville Rural King Parking Lot to Salem VDOT Park & Ridebus bus
    2. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane plane ROA - ORD
    6h 38m
    $71–314

  7. Bus to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Max Meadows to Winston Salem(Trans Center)bus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 33m
    $129–451

  8. Bus to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    6h 45m
    $107–479

  9. Bus, shuttle to Tri-Cities Regional Tn/Va Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Wytheville Rural King Parking Lot to Bristol Exit 5 Park & Ride Lotbus bus
    2. Take a shuttle bus from Low Gap to Black Bear Resortshuttle bus
    3. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Chicago O'Hare International Airport (ORD)plane plane TRI - ORD
    8h 29m
    $267–524

  10. Bus via Columbus

    1. Take the bus from Max Meadows to Columbusbus bus Greyhound US0140
    2. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    16h 39m
    $138–216

Yeager Airport (CRW) to Chicago O'Hare International Airport (ORD) flights

Calendar21Weekly Planes
Duration1h 48mAverage Duration
Ticket$42Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wytheville to Chicago.ExpandLaunch map view
  • Distance: 583.3 mi
  • Duration: 6h 24m

What companies run services between Wytheville, VA, USA and Chicago, IL, USA?

You can take a vehicle from Wytheville to Chicago via Wytheville and N Wilson Rd & Ferrell Pl - Columbus in around 16h 25m.

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