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How to get fromWytheville to Chicagoby bus, plane, car, shuttle, bus (Flixbus), or train

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There are 10 ways to get from Wytheville to Chicago by bus, plane, car, shuttle, bus (Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Roanoke Regional Airport-Woodrum Field, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Wytheville Rural King Parking Lot to Salem VDOT Park & Ridebus bus
    2. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane plane ROA - ORD
    6h 38m
    $71–314

  2. Drive to Greenbrier Valley Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Wytheville to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane plane LWB - ORD
    5h 7m
    $65–311

  3. Bus

    1. Take the bus from Wytheville to Columbusbus bus Bsb 33
    2. Take the bus from Columbus to Chicagobus bus Bsb 21 / ...
    16h 25m
    $83–187

  4. Drive  605.8 mi

    1. Drive from Wytheville to Chicagocar car 605.8 mi
    10h 38m
    $111–160

  5. Bus to Yeager Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Wytheville to Charlestonbus bus
    2. Fly from Yeager Airport (CRW) to Chicago O'Hare International Airport (ORD)plane plane CRW - ORD
    6h 33m
    $91–358

  6. Bus to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Max Meadows to Winston Salem(Trans Center)bus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 37m
    $130–462

  7. Bus to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    6h 45m
    $106–468

  8. Bus, shuttle to Tri-Cities Regional Tn/Va Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Wytheville Rural King Parking Lot to Bristol Exit 5 Park & Ride Lotbus bus
    2. Take a shuttle bus from Low Gap to Black Bear Resortshuttle bus
    3. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Chicago O'Hare International Airport (ORD)plane plane TRI - ORD
    8h 37m
    $267–514

  9. Bus via Columbus

    1. Take the bus from Wytheville to Columbusbus bus Bsb 33
    2. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    16h 35m
    $105–195

  10. Bus, train

    1. Take the bus from Max Meadows to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    16h 52m
    $231–363

Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD) flights

Calendar68Weekly Planes
Duration3h 56mAverage Duration
Ticket$48Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wytheville to Chicago.ExpandLaunch map view
  • Distance: 627.1 mi
  • Duration: 6h 38m

What companies run services between Wytheville, VA, USA and Chicago, IL, USA?

You can take a vehicle from Wytheville to Chicago via Wytheville and Columbus in around 16h 25m.

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