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How to get fromWytheville to Frederickby bus (Greyhound), bus, train, car, or plane

Find Transport to Frederick

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There are 8 ways to get from Wytheville to Frederick by bus (Greyhound), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Wytheville Rural King Parking Lot to Washington Union Stationbus bus Highlands Rhythm
    2. Take the bus from Washington Union Station to Frederick Bus Stationbus bus Greyhound US0430 / ...
    8h 40m
    $53–66

  2. Bus, train

    1. Take the bus from Wytheville Rural King Parking Lot to Christiansburgbus bus
    2. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    3. Take the train from Roanoke to Washington Union Stationtrain train
    4. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    11h 19m
    $76–167

  3. Drive  291.9 mi

    1. Drive from Wytheville to Frederickcar car 291.9 mi
    5h
    $54–77

  4. Bus to Roanoke Regional Airport-Woodrum Field, fly to Washington Dulles International Airport, bus

    1. Take the bus from Wytheville Rural King Parking Lot to Salem VDOT Park & Ridebus bus
    2. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Washington Dulles International Airport (IAD)plane plane ROA - IAD
    3. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    7h 44m
    $68–374

  5. Bus via Roanoke

    1. Take the bus from Wytheville Rural King Parking Lot to Christiansburgbus bus
    2. Take the bus from Exit 118 - Park and Ride to 3rd St Station Slip Dbus bus Swb
    3. Take the bus from Roanoke Bus Stop to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Frederick Bus Stationbus bus
    11h 51m
    $61–96

  6. Bus to Piedmont Triad International Airport, fly to Ronald Reagan Washington National Airport, bus

    1. Take the bus from Max Meadows to Winston Salem(Trans Center)bus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Ronald Reagan Washington National Airport (DCA)plane plane GSO - DCA
    3. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    7h 33m
    $158–695

  7. Bus to Charlotte Douglas International Airport, fly to Baltimore-Washington International Airport, bus

    1. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Baltimore-Washington International Airport (BWI)plane plane CLT - BWI
    3. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    8h 1m
    $204–481

  8. Bus to Piedmont Triad International Airport, fly to Washington Dulles International Airport, bus

    1. Take the bus from Max Meadows to Winston Salem(Trans Center)bus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Washington Dulles International Airport (IAD)plane plane GSO - IAD
    3. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    8h
    $131–531

Wytheville to Frederick by bus

Calendar7Weekly Buses
Duration8h 40mAverage Duration
Ticket$53Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wytheville to Frederick.ExpandLaunch map view
  • Distance: 364.2 mi
  • Duration: 8h 40m

What companies run services between Wytheville, VA, USA and Frederick, MD, USA?

You can take a bus from Wytheville Rural King Parking Lot to Frederick Bus Station via Washington Union Station in around 8h 40m.

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