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How to get fromWytheville to Lexingtonby bus, plane, or car

Find Transport to Lexington

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There are 7 ways to get from Wytheville to Lexington by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Charlotte Douglas International Airport, fly to Louisville International Airport, drive

    best
    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 4m
    $152–753

  2. Drive  266.5 mi

    cheapest
    1. Drive from Wytheville to Lexingtoncar car 266.5 mi
    5h 35m
    $46–66

  3. Bus, drive

    1. Take the bus from Max Meadows to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Corydon, INbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 9m
    $230–398

  4. Bus to Charlotte Douglas International Airport, fly to Covington, drive

    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Covington (CVG)plane plane CLT - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    7h 5m
    $143–704

  5. Bus to Charlotte Douglas International Airport, fly to Blue Grass Airport

    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    7h 59m
    $91–415

  6. Bus to Charlotte Douglas International Airport, fly to Tri-State Airport, drive

    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Tri-State Airport (HTS)plane plane CLT - HTS
    3. Drive from Tri-State Airport (HTS) to Lexingtoncar car
    7h 32m
    $104–433

  7. Bus to Roanoke Regional Airport-Woodrum Field, fly to Blue Grass Airport

    1. Take the bus from Wytheville Rural King Parking Lot to Salem VDOT Park & Ridebus bus
    2. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Blue Grass Airport (LEX)plane plane ROA - LEX
    9h 45m
    $83–383

Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF) flights

Calendar40Weekly Planes
Duration1h 53mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wytheville to Lexington.ExpandLaunch map view
  • Distance: 561.8 mi
  • Duration: 7h 4m

What companies run services between Wytheville, VA, USA and Lexington, KY, USA?

There is no direct connection from Wytheville to Lexington. However, you can take the taxi to Wytheville, take the bus to Charlotte, walk to Trade St & Graham St, take the line 34 bus to Transit Center- Bay A, walk to Transit Center- Bay V, take the line 5 bus to Charlotte Douglas Airport, walk to Charlotte Douglas International Airport (CLT) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a vehicle from Wytheville to Lexington via Max Meadows, Nashville Bus Station, Evansville, IN, Corydon, IN, S 5th @ W Jefferson, and Middletown Station @ Target in around 17h 9m.

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