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How to get fromWytheville to Pittsburghby bus (Greyhound), bus, train, car, plane, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Wytheville to Pittsburgh by bus (Greyhound), bus, train, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Cambridge

    best
    1. Take the bus from Wytheville to Charlestonbus bus
    2. Take the bus from Charleston to Cambridgebus bus
    3. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    9h 30m
    $68–160

  2. Bus

    cheapest
    1. Take the bus from Wytheville to Charlestonbus bus
    2. Take the bus from Charleston to Morgantown Mt Linebus bus
    3. Take the bus from Westover Terminal to Pittsburgh Greyhoundbus bus
    10h 30m
    $54–162

  3. Bus, train

    1. Take the bus from Wytheville Rural King Parking Lot to Washington Union Stationbus bus Highlands Rhythm
    2. Take the train from Washington Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    15h 18m
    $206–305

  4. Drive  307.6 mi

    1. Drive from Wytheville to Pittsburghcar car 307.6 mi
    5h 20m
    $57–82

  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Wytheville to Charlottebus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Pittsburgh International Airport (PIT)plane plane CLT - PIT
    7h
    $109–533

  6. Bus via Washington

    1. Take the bus from Wytheville Rural King Parking Lot to Washington Union Stationbus bus Highlands Rhythm
    2. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    13h 20m
    $81–120

  7. Bus to Roanoke Regional Airport-Woodrum Field, fly

    1. Take the bus from Wytheville Rural King Parking Lot to Salem VDOT Park & Ridebus bus
    2. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Pittsburgh International Airport (PIT)plane plane ROA - PIT
    8h 41m
    $89–449

  8. Bus to Piedmont Triad International Airport, fly

    1. Take the bus from Max Meadows to Winston Salem(Trans Center)bus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Pittsburgh International Airport (PIT)plane plane GSO - PIT
    8h 35m
    $154–638

Wytheville to Pittsburgh by bus and train

Calendar7Weekly Services
Duration15h 18mAverage Duration
Ticket$206Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wytheville to Pittsburgh.ExpandLaunch map view
  • Distance: 404.6 mi
  • Duration: 9h 30m

What companies run services between Wytheville, VA, USA and Pittsburgh, PA, USA?

You can take a vehicle from Wytheville to Pittsburgh Intermodal Station via Wytheville, Charleston, and Cambridge, OH in around 9h 30m.

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Bus operators

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