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How to get fromWytheville to Pittsburghby bus (Greyhound), bus, train, car, plane, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Wytheville to Pittsburgh by bus (Greyhound), bus, train, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Wytheville to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Cambridgebus bus
    3. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    9h 29m
    $66–163

  2. Drive 307.6 mi

    cheapest
    1. Drive from Wytheville to Pittsburghcar car 307.6 mi
    5h 20m
    $57–82

  3. Bus, train

    1. Take the bus from Wytheville Rural King Parking Lot to Washington Union Stationbus bus Highlands Rhythm
    2. Take the train from Washington Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    15h 18m
    $141–245

  4. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Pittsburgh International Airport (PIT)plane plane CLT - PIT
    7h 8m
    $115–534

  5. Bus via Washington

    1. Take the bus from Wytheville Rural King Parking Lot to Washington Union Stationbus bus Highlands Rhythm
    2. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0430 / ...
    12h 50m
    $81–125

  6. Bus via Washington #2

    1. Take the bus from Rural King Shopping Center to DC Union Stationbus bus Virginia Breeze
    2. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0430 / ...
    13h
    $77–139

  7. Bus, bus to Roanoke Regional Airport-Woodrum Field, fly

    1. Take the bus from Rural King Shopping Center to Route 460 Park and Ridebus bus
    2. Take the bus from Exit 118 - Park and Ride to Airportbus bus
    3. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Pittsburgh International Airport (PIT)plane plane ROA - PIT
    8h 30m
    $77–400

Wytheville to Pittsburgh by bus and train

Calendar7Weekly Services
Duration15h 18mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Wytheville to Pittsburgh.ExpandLaunch map view
  • Distance: 385.5 mi
  • Duration: 9h 29m

What companies run services between Wytheville, VA, USA and Pittsburgh, PA, USA?

You can take a vehicle from Wytheville to Pittsburgh Intermodal Station via Wytheville, Charleston, WV, Cambridge, and Cambridge, OH in around 9h 29m.

Airlines
Train operators
Bus operators

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