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How to get fromYork to Des Moinesby plane, bus, train, bus (Flixbus, Greyhound), car, subway, or bus (Greyhound)

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There are 11 ways to get from York to Des Moines by plane, bus, train, bus (Flixbus, Greyhound), car, subway, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Des Moines (DSM)plane plane MDT - DSM
    7h 12m
    $332–1,530

  2. Bus via Indianapolis (Greyhound)

    cheapest
    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    25h 45m
    $159–317

  3. Bus, train via Pittsburgh

    1. Take the bus from York Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    24h 42m
    $264–554

  4. Bus

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    25h 30m
    $174–317

  5. Drive 990.1 mi

    1. Drive from York to Des Moinescar car 990.1 mi
    16h 19m
    $181–261

  6. Bus, bus to Ronald Reagan Washington National Airport, fly

    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore to Union Stationbus bus
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    6h 46m
    $284–1,263

  7. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)plane plane BWI - DSM
    8h 5m
    $197–888

  8. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    7h 51m
    $274–1,201

  9. Bus, train, subway to Washington Dulles International Airport, fly

    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Take the train from West Baltimore to New Carrollton Amtrak Stationtrain train
    3. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Des Moines (DSM)plane plane IAD - DSM
    9h 55m
    $171–800

  10. Train, bus

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    27h 16m
    $309–667

  11. Bus, train

    1. Take the bus from York Bus Stop to Washington Union Stationbus bus
    2. Take the train from Washington Union Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 7m
    $304–676

York to Des Moines by bus and train

Calendar7Weekly Services
Duration24h 42mAverage Duration
Ticket$264Cheapest Price
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Questions & Answers

Map of how to get from York to Des Moines.ExpandLaunch map view
  • Distance: 926.2 mi
  • Duration: 7h 12m

What companies run services between York, PA, USA and Des Moines, IA, USA?

United Airlines, Delta, and American Airlines fly from Harrisburg International Airport (MDT) to Des Moines (DSM) hourly. Alternatively, you can take a bus from York Bus Stop to Des Moines via Harrisburg Bus Station and Chicago Bus Station in around 25h 30m.

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