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How to get fromYork to St. Louisby bus, plane, bus (Greyhound), train (Amtrak), car, train, or subway

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There are 8 ways to get from York to St. Louis by bus, plane, bus (Greyhound), train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly

    best
    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    6h 25m
    $143–671

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    19h 35m
    $124–247

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    23h 31m
    $319–687

  4. Drive 798 mi

    1. Drive from York to St. Louiscar car 798 mi
    13h 38m
    $146–211

  5. Bus, bus to Ronald Reagan Washington National Airport, fly

    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore to Union Stationbus bus
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    6h 45m
    $180–426

  6. Fly from Harrisburg International Airport

    1. Fly from Harrisburg International Airport (MDT) to Lambert–St. Louis International Airport (STL)plane plane MDT - STL
    7h 32m
    $248–1,212

  7. Bus, train, subway to Washington Dulles International Airport, fly

    1. Take the bus from York Bus Stop to Baltimore Downtown Bus Stationbus bus
    2. Take the train from West Baltimore to New Carrollton Amtrak Stationtrain train
    3. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    8h 8m
    $197–1,033

  8. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    7h 50m
    $190–883

York to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration19h 35mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from York to St. Louis.ExpandLaunch map view
  • Distance: 814.2 mi
  • Duration: 6h 25m

What companies run services between York, PA, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Harrisburg Bus Station to St Louis Bus Station twice daily. Tickets cost $120–240 and the journey takes 18h 5m. Alternatively, you can take a bus from York Bus Stop to St. Louis via Harrisburg Bus Station, Harrisburg, Pittsburgh Amtrak Station, and Chicago Union Station in around 23h 31m.

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