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How to get fromYorkville to Mayo Clinicby train, plane, bus, or car

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There are 8 ways to get from Yorkville to Mayo Clinic by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from Plano Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    6h 6m
    $74–389

  2. Drive 330.8 mi

    cheapest
    1. Drive from Yorkville to Mayo Cliniccar car 330.8 mi
    5h 46m
    $61–88

  3. Train, bus via Milwaukee

    1. Take the train from Plano Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 40m
    $127–209

  4. Train, bus

    1. Take the train from Plano Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    12h 27m
    $179–364

  5. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Plano Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 50m
    $305–561

  6. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Plano Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 39m
    $158–564

  7. Train, bus #2

    1. Take the train from Aurora to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 41m
    $110–173

  8. Train, bus #3

    1. Take the train from Aurora to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 57m
    $110–168

Chicago O'Hare International Airport (ORD) to Rochester (RST) flights

Calendar35Weekly Planes
Duration1h 53mAverage Duration
Ticket$43Cheapest Price
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Questions & Answers

Map of how to get from Yorkville to Mayo Clinic.ExpandLaunch map view
  • Distance: 353.2 mi
  • Duration: 6h 6m

What companies run services between Yorkville, IL, USA and Mayo Clinic, MN, USA?

There is no direct connection from Yorkville to Mayo Clinic. However, you can take the taxi to Plano Station, take the train to Chicago Union Station, walk to LaSalle, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Rochester (RST), walk to Rochester - Airport, take the shuttle to Rochester, then walk to Mayo Clinic. Alternatively, you can take a vehicle from Yorkville to Mayo Clinic via Plano Station, Chicago Union Station, Milwaukee, Milwaukee, and Rochester in around 10h 40m.

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