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How to get fromYoungstown to Knoxvilleby bus, plane, bus (Flixbus), car, bus (Greyhound), train, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Youngstown to Knoxville by bus, plane, bus (Flixbus), car, bus (Greyhound), train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Cleveland-Hopkins International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Youngstown Bus Stop to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Mcghee Tyson Airport (TYS)plane plane CLE - TYS
    6h 59m
    $222–948

  2. Drive 529 mi

    cheapest
    1. Drive from Youngstown to Knoxvillecar car 529 mi
    8h 52m
    $97–140

  3. Bus

    1. Take the bus from Youngstown Bus Stop to Newark Penn Stationbus bus FlixBus N2641
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    21h 29m
    $204–278

  4. Bus to Pittsburgh International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS)plane plane PIT - TYS
    7h 48m
    $196–840

  5. Bus to Akron, fly to Mcghee Tyson Airport

    1. Take the bus from Youngstown to Akronbus bus
    2. Fly from Akron (CAK) to Mcghee Tyson Airport (TYS)plane plane CAK - TYS
    8h 2m

  6. Bus to Pittsburgh International Airport, fly to Nashville, drive

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 10m
    $641–1,170

  7. Bus via Pittsburgh

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    23h 2m
    $259–403

  8. Bus, train

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    25h 12m
    $289–473

  9. Bus via Pittsburgh #2

    1. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    28h 45m
    $180–255

Cleveland-Hopkins International Airport (CLE) to Mcghee Tyson Airport (TYS) flights

Calendar111Weekly Planes
Duration4h 24mAverage Duration
Ticket$152Cheapest Price
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Questions & Answers

Map of how to get from Youngstown to Knoxville.ExpandLaunch map view
  • Distance: 504.1 mi
  • Duration: 6h 59m

What companies run services between Youngstown, OH, USA and Knoxville, TN, USA?

You can take a bus from Youngstown Bus Stop to Knoxville via Newark, Penn Station, Newark Penn Station, Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 21h 29m.

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