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How to get fromYpsilanti to Chicagoby train (Amtrak), bus (Amtrak), car, bus, plane, or train

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There are 7 ways to get from Ypsilanti to Chicago by train (Amtrak), bus (Amtrak), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Dearborn to Chicago Union Stationtrain train Wolverine
    5h 18m
    $210–313

  2. Drive  249.1 mi

    cheapest
    1. Drive from Ypsilanti to Chicagocar car 249.1 mi
    4h 9m
    $46–66

  3. Bus

    1. Take the bus from Ann Arbor to East Lansingbus bus It 44
    2. Take the bus from East Lansing Amtrak Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    8h 22m

  4. Line 4 bus, bus, fly to Chicago Midway International Airport

    1. Take the bus from YTC - Stop 2 to Blake Transit Centerbus bus
    2. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    3. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    5h 16m
    $76–494

  5. Bus, train

    1. Take the bus from Ann Arbor to East Lansingbus bus It 44
    2. Take the train from East Lansing Amtrak Station to Chicago Union Stationtrain train Blue Water
    8h 22m
    $124–212

  6. Line 4 bus, bus, fly to Chicago O'Hare International Airport

    1. Take the bus from YTC - Stop 2 to Blake Transit Centerbus bus
    2. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    3. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    5h 37m
    $140–774

  7. Bus, fly to South Bend, train

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    2. Fly from Detroit (DTW) to South Bend (SBN)plane plane DTW - SBN
    3. Take the train from South Bend Airport to Van Buren St.train train
    7h 9m
    $78–476

Detroit (DTW) to Chicago Midway International Airport (MDW) flights

Calendar50Weekly Planes
Duration1h 14mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ypsilanti to Chicago.ExpandLaunch map view
  • Distance: 290.5 mi
  • Duration: 5h 18m

What companies run services between Ypsilanti, MI, USA and Chicago, IL, USA?

Amtrak operates a train from Dearborn to Chicago Union Station 3 times a day. Tickets cost $140–230 and the journey takes 4h 48m. Alternatively, you can take a bus from YTC - Stop 2 to Chicago Union Station via Ann Arbor, East Lansing, and East Lansing Amtrak Station in around 8h 22m.

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