There are 7 ways to get from Ypsilanti to Des Moines by car, plane, train, bus, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Capital Region International Airport, fly
best- Drive from Ypsilanti to Lansing-Airport-LANcar
- Fly from Capital Region International Airport (LAN) to Des Moines (DSM)plane LAN - DSM
5h 42m$92–403Train, bus
- Take the train from Dearborn to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
14h 49m$330–513Bus
- Take the bus from Ann Arbor to East Lansingbus
- Take the bus from East Lansing Amtrak Station to Chicago Union Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
16h 1mDrive 563.9 mi
- Drive from Ypsilanti to Des Moinescar 563.9 mi
9h 21m$100–144Bus to Detroit, fly
- Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus
- Fly from Detroit (DTW) to Des Moines (DSM)plane DTW - DSM
5h 30m$122–642Bus, train
- Take the bus from Ann Arbor to East Lansingbus
- Take the train from East Lansing Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
16h 1m$184–306Bus, train via Galesburg
- Take the bus from Ann Arbor to East Lansingbus
- Take the train from East Lansing Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
17h 53m$244–412
Capital Region International Airport (LAN) to Des Moines (DSM) flights
Comparing Your Travel Options
The cheapest way to get from Ypsilanti to Des Moines is to drive which costs $95 - $150 and takes 9h 21m.
The fastest way to get from Ypsilanti to Des Moines is to bus and fly which takes 5h 30m and costs $120 - $650.
No, there is no direct bus from Ypsilanti to Des Moines. However, there are services departing from YTC - Stop 2 and arriving at Des Moines via Ann Arbor, East Lansing Amtrak Station and Chicago Bus Station. The journey, including transfers, takes approximately 16h 1m.
The distance between Ypsilanti and Des Moines is 558 miles. The road distance is 567.2 miles.
The best way to get from Ypsilanti to Des Moines without a car is to train and bus which takes 14h 49m and costs $330 - $550.
It takes approximately 5h 42m to get from Ypsilanti to Des Moines, including transfers.
Ypsilanti to Des Moines bus services, operated by Indian Trails, depart from Ann Arbor station.
Ypsilanti to Des Moines bus services, operated by Indian Trails, arrive at East Lansing station.
Des Moines is 1h behind Ypsilanti. It is currently 6:57 AM in Ypsilanti and 5:57 AM in Des Moines.
Yes, the driving distance between Ypsilanti to Des Moines is 567 miles. It takes approximately 9h 21m to drive from Ypsilanti to Des Moines.
What companies run services between Ypsilanti, MI, USA and Des Moines, IA, USA?
You can take a bus from YTC - Stop 2 to Des Moines via Ann Arbor, East Lansing, East Lansing Amtrak Station, Chicago Union Station, and Chicago Bus Station in around 16h 1m.
- Website
- delta.com
Flights from Capital Region International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $65–380
Flights from Detroit to Des Moines
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $95–600
Flights from Detroit to Des Moines via Minneapolis
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Capital Region International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $60–360
Flights from Capital Region International Airport to Des Moines via Reagan Washington
- Ave. Duration
- 9h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Detroit to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $95–600
- Website
- united.com
Flights from Detroit to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $95–600
- Website
- southwest.com
Flights from Detroit to Des Moines via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $95–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Dearborn to Chicago Union Station
- Ave. Duration
- 4h 48m
- Frequency
- 3 times a day
- Estimated price
- $140–230
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from East Lansing Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 51m
- Frequency
- Once daily
- Estimated price
- $110–180
- Website
- Amtrak
Train from East Lansing Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 51m
- Frequency
- Once daily
- Estimated price
- $110–180
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Ann Arbor to East Lansing
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–30
- Website
- Indian Trails
Bus from Ann Arbor to East Lansing
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–30
- Website
- Indian Trails
Bus from Ann Arbor to East Lansing
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–30
- Website
- Indian Trails
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from East Lansing Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 51m
- Frequency
- Once a week
- Website
- Amtrak
- Phone
- +1 517-333-0400
- [email protected]
- Website
- Michigan Flyer
Bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airport
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Michigan Flyer
- Child 2-16
- $7–9
- Adult
- $10–15
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Booking & Getting There
There are 238+ hotels available in Des Moines.






