Rome2Rio

How to get fromYpsilanti to Louisvilleby bus, plane, bus (Greyhound), train, car, or bus (Amtrak, Greyhound)

Find Transport to Louisville

See all options

There are 7 ways to get from Ypsilanti to Louisville by bus, plane, bus (Greyhound), train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 4 bus, bus, fly to Louisville International Airport

    best
    1. Take the bus from YTC - Stop 2 to Blake Transit Centerbus bus
    2. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    3. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    5h 58m
    $90–570

  2. Drive 343.7 mi

    cheapest
    1. Drive from Ypsilanti to Louisvillecar car 343.7 mi
    5h 50m
    $63–91

  3. Bus

    1. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit - Grand Circus Parkbus bus Ann Arbor to Detroit
    2. Take the bus from Detroit Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    10h 48m
    $66–122

  4. Train, bus

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    13h 15m
    $187–371

  5. Bus, fly to Blue Grass Airport, drive

    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 3m
    $142–836

  6. Bus, fly to Covington

    1. Take the bus from Blake Transit Center to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Covington (CVG)plane plane DTW - CVG
    3. Take the bus from Cincinnati to Louisvillebus bus
    8h 23m
    $920–1,364

  7. Bus via Toledo

    1. Take the bus from Ann Arbor Amtrak Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus Greyhound US0135 / ...
    11h 22m
    $78–144

Ypsilanti to Louisville by bus and foot

Calendar21Weekly Services
Duration10h 48mAverage Duration
Ticket$66Cheapest Price
See schedules

Questions & Answers

Map of how to get from Ypsilanti to Louisville.ExpandLaunch map view
  • Distance: 345.9 mi
  • Duration: 5h 58m

What companies run services between Ypsilanti, MI, USA and Louisville, KY, USA?

You can take a bus from YTC - Stop 2 to Louisville Bus Station via Blake Transit Center, Ann Arbor- Blake Transit Ctr., MI, Detroit - Grand Circus Park, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, and Detroit Bus Station in around 10h 48m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound