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How to get fromYpsilanti to St. Louisby car, plane, train (Amtrak), bus, train, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Ypsilanti to St. Louis by car, plane, train (Amtrak), bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Capital Region International Airport, fly

    best
    1. Drive from Ypsilanti to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Lambert–St. Louis International Airport (STL)plane plane LAN - STL
    5h 36m
    $127–723

  2. Bus

    cheapest
    1. Take the bus from Ann Arbor to Chicago Bus Stationbus bus Greyhound US0160
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    14h 17m
    $84–144

  3. Train (Amtrak)

    1. Take the train from Ann Arbor Amtrak Station to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    10h 17m
    $160–356

  4. Bus, train (Amtrak)

    1. Take the bus from Ann Arbor Amtrak Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    12h 47m
    $138–274

  5. Drive  501.2 mi

    1. Drive from Ypsilanti to St. Louiscar car 501.2 mi
    8h 29m
    $92–133

  6. Line 4 bus, bus to Detroit, fly

    1. Take the bus from YTC - Stop 2 to Blake Transit Centerbus bus
    2. Take the bus from Ann Arbor- Blake Transit Ctr., MI to Detroit Metro Airportbus bus
    3. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 37m
    $612–972

Ypsilanti to St. Louis by bus and train (Amtrak)

Calendar1Weekly Services
Duration12h 47mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Ypsilanti to St. Louis.ExpandLaunch map view
  • Distance: 501.8 mi
  • Duration: 5h 36m

What companies run services between Ypsilanti, MI, USA and St. Louis, MO, USA?

You can take a vehicle from Ypsilanti to St. Louis via Ann Arbor Amtrak Station and Chicago Union Station in around 10h 17m. Alternatively, you can take a bus from YTC - Stop 2 to St Louis Bus Station via Blake Transit Center, BTC - Fourth Ave Stop 4, Amtrak Station, Ann Arbor, and Chicago Bus Station in around 14h 17m.

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