There are 5 ways to get from Zapotillo (Region) to Guayaquil by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Machala
best- Take the bus from Paletillas to Huaquillasbus
- Take the bus from Huaquillas to Machalabus
- Take the bus from Machala to Terminal Terrestre de Guayaquilbus
8h 41m$29–46Drive 356.8 km
cheapest- Drive from Zapotillo (Region) to Guayaquilcar 356.8 km
5h 14m$21–30Bus, fly
- Take the bus from Paletillas to Huaquillasbus
- Take the bus from Huaquillas to Cuencabus
- Fly from Cuenca (CUE) to José Joaquín De Olmedo International Airport (GYE)plane CUE - GYE
10h 23m$101–216Bus
- Take the bus from La Ceiba to Terminal Terrestre de Guayaquilbus Zapotillo / ...
23h 57m$34–44Drive, bus
- Drive from Zapotillo (Region) to Tumbescar
- Take the bus from Tumbes to Terminal Terrestre de Guayaquilbus Lima / ...
6h 39m$34–46
Cuenca (CUE) to José Joaquín De Olmedo International Airport (GYE) flights
Questions & Answers
The cheapest way to get from Zapotillo (Region) to Guayaquil is to drive which costs $20 - $30 and takes 5h 14m.
The fastest way to get from Zapotillo (Region) to Guayaquil is to drive which takes 5h 14m and costs $20 - $30.
No, there is no direct bus from Zapotillo (Region) to Guayaquil. However, there are services departing from Paletillas and arriving at Terminal Terrestre de Guayaquil via Huaquillas and Machala. The journey, including transfers, takes approximately 8h 41m.
The distance between Zapotillo (Region) and Guayaquil is 436 km. The road distance is 356.8 km.
The best way to get from Zapotillo (Region) to Guayaquil without a car is to bus via Machala which takes 8h 41m and costs $28 - $50.
It takes approximately 8h 41m to get from Zapotillo (Region) to Guayaquil, including transfers.
Zapotillo (Region) to Guayaquil bus services, operated by Unión Cariamanga Internacional, depart from Paletillas station.
Zapotillo (Region) to Guayaquil bus services, operated by Unión Cariamanga Internacional, arrive at Huaquillas station.
Yes, the driving distance between Zapotillo (Region) to Guayaquil is 357 km. It takes approximately 5h 14m to drive from Zapotillo (Region) to Guayaquil.
There are 456+ hotels available in Guayaquil.
What companies run services between Zapotillo (Region), Ecuador and Guayaquil, Ecuador?
You can take a vehicle from Zapotillo (Region) to Terminal Terrestre de Guayaquil via Paletillas, Huaquillas, Huaquillas, and Machala in around 8h 41m.
- Website
- latam.com
Flights from Cuenca to José Joaquín De Olmedo International Airport
- Ave. Duration
- 45 min
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $80–180
- Phone
- +593 98 166 2733
- [email protected]
- Website
- facebook.com
Bus from Paletillas to Huaquillas
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $6–9
- Schedules at
- boletos.unioncariamanga.com
- Book at
- boletos.unioncariamanga.com
Bus from Paletillas to Huaquillas
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $6–9
- Schedules at
- boletos.unioncariamanga.com
- Book at
- boletos.unioncariamanga.com
- [email protected]
- Website
- reina-del-camino.com
Bus from Huaquillas to Machala
- Ave. Duration
- 57 min
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- https://www.facebook.com/ReinadelCaminoOficial
- Phone
- +593 07 293 1164
- [email protected]
- Website
- facebook.com
Bus from Machala to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $8
- Website
- https://www.facebook.com/ecuatoriano.pullman/
- Phone
- +593 95 874 8163
- [email protected]
- Website
- cifainternacional.com
Bus from Machala to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $7–15
- Schedules at
- cifainternacional.com
- Phone
- +593-07 2823163
- [email protected]
- Website
- transportesazuay.com
Bus from Huaquillas to Cuenca
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $8–19
- Schedules at
- transportesazuay.com
- Phone
- +59 07 257 1861
- [email protected]
- Website
- cooperativaloja.com.ec
Bus from La Ceiba to Terminal Terrestre de Guayaquil
- Ave. Duration
- 23h 17m
- Frequency
- Twice daily
- Estimated price
- $13–19
- Schedules at
- cooperativaloja.com.ec
- Book at
- api.whatsapp.com
- Phone
- +51 1 311-5050
- Website
- cruzdelsur.com.pe
Bus from Tumbes to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 16m
- Frequency
- Twice daily
- Estimated price
- $13–15
- Website
- https://www.cruzdelsur.com.pe/home-en/
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