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How to get fromZephyrhills to Florida Keysby car, plane, train, bus, shuttle, taxi, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Zephyrhills to Florida Keys by car, plane, train, bus, shuttle, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Key West International Airport

    best
    1. Drive from Zephyrhills to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    6h 21m
    $128–367

  2. Drive 374.4 mi

    cheapest
    1. Drive from Zephyrhills to Florida Keyscar car 374.4 mi
    7h 37m
    $69–99

  3. Train, bus

    1. Take the train from Lakeland to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 16m
    $194–306

  4. Bus, shuttle

    1. Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus bus Tallahassee
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    14h 51m
    $222–320

  5. Taxi, train, train to Orlando, fly to Key West International Airport, bus

    1. Take the taxi from Zephyrhills to Lakeland Amtrak Stationtaxi taxi
    2. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    3. Take the train from Kissimmee to Sand Lake Roadtrain train
    4. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    7h 58m
    $271–911

  6. Bus to Tampa, fly to Key West International Airport, bus

    1. Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    8h 26m
    $176–528

  7. Fly Tampa to Miami International Airport, shuttle

    1. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 55m
    $932–1,328

  8. Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport

    1. Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus bus
    2. Take a shuttle bus from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminalshuttle bus
    3. Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus bus
    4. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    5. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    10h 21m
    $148–384

  9. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    16h 41m
    $72–140

Zephyrhills to Florida Keys by bus, shuttle, and foot

Calendar7Weekly Services
Duration14h 51mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

Map of how to get from Zephyrhills to Florida Keys.ExpandLaunch map view
  • Distance: 401.5 mi
  • Duration: 6h 21m

What companies run services between Zephyrhills, FL, USA and Florida Keys, FL, USA?

You can take a bus from Zephyrhills Downtown Transfer Station to Florida Keys via Wiregrass Park n Ride, Marion Transit Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 41m.

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