There are 10 ways to get from Zephyrhills to Florida Keys by train, bus, shuttle, car, plane, bus (Flixbus, Greyhound), or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Lakeland to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 16m$182–291Bus
cheapest- Take the bus from University of South Florida to Miami Airport Stationbus FlixBus 2421
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
16h 31m$66–114Bus, shuttle
- Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
14h 28m$218–320Drive 374.5 mi
- Drive from Zephyrhills to Florida Keyscar 374.5 mi
7h 37m$69–99Bus to Tampa, fly to Key West International Airport, bus
- Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
8h 22m$162–468Taxi, train, train to Orlando, fly to Key West International Airport, bus
- Take the taxi from Zephyrhills to Lakeland Amtrak Stationtaxi
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
8h 6m$269–908Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Zephyrhills to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
6h 24m$128–357Fly Tampa to Miami International Airport, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 52m$832–1,328Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport
- Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus
- Take a shuttle bus from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminal
- Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
10h 20m$142–374Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 21m$302–798
Zephyrhills to Florida Keys by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from Zephyrhills to Florida Keys is to bus which costs $65 - $120 and takes 16h 31m.
The fastest way to get from Zephyrhills to Florida Keys is to drive and fly which takes 6h 24m and costs $120 - $360.
No, there is no direct bus from Zephyrhills station to Florida Keys. However, there are services departing from Zephyrhills Downtown Transfer Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Wiregrass Park n Ride, UATC to MSC, University of South Florida, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 16h 31m.
The distance between Zephyrhills and Florida Keys is 394 miles. The road distance is 376.7 miles.
The best way to get from Zephyrhills to Florida Keys without a car is to train and bus which takes 12h 16m and costs $180 - $300.
It takes approximately 12h 16m to get from Zephyrhills to Florida Keys, including transfers.
Zephyrhills to Florida Keys bus services, operated by Flixbus USA, depart from University of South Florida station.
Zephyrhills to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Zephyrhills to Florida Keys is 377 miles. It takes approximately 7h 37m to drive from Zephyrhills to Florida Keys.
There are 972+ hotels available in Florida Keys.
What companies run services between Zephyrhills, FL, USA and Florida Keys, FL, USA?
You can take a bus from Zephyrhills Downtown Transfer Station to Florida Keys via Wiregrass Park n Ride, UATC to MSC, University of South Florida, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 31m.
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $35–250
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $30–230
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $40–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Lakeland to Delray Beach Amtrak
- Ave. Duration
- 3h 34m
- Frequency
- Once daily
- Estimated price
- $45–110
- Website
- Amtrak
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $11–25
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
- Ave. Duration
- 35 min
- Estimated price
- $110–140
Wesley Chapel Taxi
- Phone
- +1-813-995-7030
- Website
- wesleychapeltaxi.com
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