Rome2Rio

How to get fromZephyrhills to Key Westby bus, plane, ferry, car, train, or shuttle

Find Transport to Key West

See all options

There are 8 ways to get from Zephyrhills to Key West by bus, plane, ferry, car, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly

    best
    1. Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    5h 35m
    $106–446

  2. Drive to Orlando Sanford, fly

    cheapest
    1. Drive from Zephyrhills to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 38m
    $62–276

  3. Bus, ferry

    1. Take the bus from Dade City to Fort Myersbus bus Houston
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    10h 50m
    $232–266

  4. Drive 389.9 mi

    1. Drive from Zephyrhills to Key Westcar car 389.9 mi
    8h
    $72–103

  5. Train to Orlando, fly

    1. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h 19m
    $209–828

  6. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Dade City to Bradentonbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane plane SRQ - EYW
    9h 31m
    $110–428

  7. Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly

    1. Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ridebus bus
    2. Take a shuttle bus from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminalshuttle bus
    3. Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus bus
    4. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    7h 33m
    $76–302

  8. Train, bus

    1. Take the train from Lakeland to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 2m
    $187–291

Tampa (TPA) to Key West International Airport (EYW) flights

Calendar20Weekly Planes
Duration2h 15mAverage Duration
Ticket$38Cheapest Price
See schedules

Questions & Answers

Map of how to get from Zephyrhills to Key West.ExpandLaunch map view
  • Distance: 290 mi
  • Duration: 5h 35m

What companies run services between Zephyrhills, FL, USA and Key West, FL, USA?

There is no direct connection from Zephyrhills to Key West. However, you can take the bus to Wiregrass Park and Ride, take the bus to SR 56 & Cypress Ridge Blvd, walk to Gate Gas Station Wesley Chapel, take the shuttle to Tampa International Airport - Red Terminal, walk to Tampa (TPA) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a bus from Zephyrhills Downtown Transfer Station to Key West, FL via 5th St & Martin Luther King Blvd, Dade City, Fort Myers, and Fort Myers Beach, FL in around 10h 50m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound