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How to get fromZephyrhills to Panama Cityby car, plane, train, or bus

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There are 6 ways to get from Zephyrhills to Panama City by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive 319.7 mi

    best
    1. Drive from Zephyrhills to Panama Citycar car 319.7 mi
    6h 22m
    $59–85

  2. Fly Tampa to Northwest Florida Beaches International Airport

    1. Fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP)plane plane TPA - ECP
    8h 21m
    $164–524

  3. Train to Orlando, fly to Northwest Florida Beaches International Airport

    1. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Northwest Florida Beaches International Airport (ECP)plane plane MCO - ECP
    8h 1m
    $253–597

  4. Train to Orlando, fly to Pensacola International Airport, drive

    1. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Pensacola International Airport (PNS)plane plane MCO - PNS
    3. Drive from Pensacola-Airport-PNS to Panama Citycar car
    7h 56m
    $227–896

  5. Fly Tampa to Pensacola International Airport, drive

    1. Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane plane TPA - PNS
    2. Drive from Pensacola-Airport-PNS to Panama Citycar car
    8h 22m
    $208–512

  6. Bus to Sarasota–Bradenton International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Dade City to Bradentonbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Northwest Florida Beaches International Airport (ECP)plane plane SRQ - ECP
    11h 29m
    $214–746

Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar86Weekly Planes
Duration5h 28mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Zephyrhills to Panama City.ExpandLaunch map view
  • Distance: 319.7 mi
  • Duration: 6h 22m

What companies run services between Zephyrhills, FL, USA and Panama City, FL, USA?

Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

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