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How to get fromAntigua Guatemala to Panamaby bus, plane, car, or shuttle

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There are 7 ways to get from Antigua Guatemala to Panama by bus, plane, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to La Aurora International Airport, fly to Tocumen International Airport

    best
    1. Take the bus from Antigua Guatemala to Terminal de Autobusesbus bus
    2. Fly from La Aurora International Airport (GUA) to Tocumen International Airport (PTY)plane plane GUA - PTY
    6h 47m
    $232–442

  2. Fly La Aurora International Airport to David

    cheapest
    1. Fly from La Aurora International Airport (GUA) to David (DAV)plane plane GUA - DAV
    8h 35m
    $135–616

  3. Bus via Escuintla

    1. Take the bus from Escuintla to San Salvadorbus bus
    2. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    3. Take the bus from Terminal Tica Bus to Terminal Albrookbus bus
    44h

  4. Drive 1,883.1 km

    1. Drive from Antigua Guatemala to Panama Citycar car 1,883.1 km
    28h 39m
    $258–373

  5. Shuttle to Cuscatlán International Airport, fly to Tocumen International Airport

    1. Take a shuttle bus from Antigua Guatemala to San Salvadorshuttle bus
    2. Fly from Cuscatlán International Airport (SAL) to Tocumen International Airport (PTY)plane plane SAL - PTY
    10h 33m
    $480–690

  6. Shuttle, bus

    1. Take a shuttle bus from Antigua Guatemala to San Salvadorshuttle bus
    2. Take the bus from San Salvador to San Josébus bus
    3. Take a shuttle bus from San José to Paso Canoasshuttle bus
    4. Take the bus from Frontera to Albrook - Panamabus bus
    45h 43m
    $731–734

  7. Bus

    1. Take the bus from Guatemala Estación Zona 10 to Terminal San Carlos - Ticabusbus bus
    2. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    3. Take the bus from Terminal Tica Bus to Terminal Albrookbus bus
    2d 2h
    $160–233

La Aurora International Airport (GUA) to Tocumen International Airport (PTY) flights

Calendar64Weekly Planes
Duration3h 20mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Antigua Guatemala to Panama.ExpandLaunch map view
  • Distance: 1,421.7 km
  • Duration: 6h 47m

What companies run services between Antigua Guatemala and Panama?

You can take a bus from Antigua Guatemala to Fernandez de Cordoba via Escuintla, Escuintla, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, Terminal Tica Bus, Terminal Albrook, and Albrook in around 44h. Alternatively, Copa Airlines flies from La Aurora International Airport (GUA) to David (DAV) 4 times a day.

Airlines
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