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How to get fromCancún to Panama Cityby plane, bus, car, or shuttle

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There are 5 ways to get from Cancún to Panama City by plane, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Cancún International Airport (CUN) to Tocumen International Airport (PTY)plane plane CUN - PTY
    5h 38m
    $240–445

  2. Bus via Belize City

    1. Take the bus from Terminal de Autobuses ADO Cancún to Chetumalbus bus
    2. Take the bus from Chetumal to Belize Citybus bus
    3. Take the bus from Belize City to San Salvadorbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 16h
    $285–1,201

  3. Drive 2,710.1 km

    1. Drive from Cancún to Panama Citycar car 2,710.1 km
    44h 46m
    $371–536

  4. Shuttle, bus

    1. Take a shuttle bus from Cancún to Belize Cityshuttle bus
    2. Take a shuttle bus from Belize City to Antigua Guatemalashuttle bus
    3. Take a shuttle bus from Antigua Guatemala to San Salvadorshuttle bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 19h

  5. Bus

    1. Take the bus from Terminal de Autobuses ADO Cancún to Tapachulabus bus
    2. Take the bus from Tapachula to Guatemana Aguilar Batresbus bus
    3. Take the bus from Guatemala Aguilar Batres to Terminal San Carlos - Ticabusbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    5. Take the bus from Terminal Tica Bus to Terminal Albrookbus bus
    3d 7h
    $283–503

Cancún International Airport (CUN) to Tocumen International Airport (PTY) flights

Calendar40Weekly Planes
Duration2h 40mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Cancún to Panama City.ExpandLaunch map view
  • Distance: 1,586.6 km
  • Duration: 5h 38m

What companies run services between Cancún, Mexico and Panama City, Panama?

Copa Airlines flies from Cancún International Airport (CUN) to Tocumen International Airport (PTY) every 4 hours. Alternatively, you can take a bus from Terminal de Autobuses ADO Cancún to Terminal Tica Bus Panamá via Chetumal, Belize City, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 2d 16h.

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