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How to get fromCape Coral to Panama Cityby bus, plane, or car

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There are 6 ways to get from Cape Coral to Panama City by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Miami International Airport, fly

    best
    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Tocumen International Airport (PTY)plane plane MIA - PTY
    10h 59m
    $284–536

  2. Fly from Ft. Myers

    cheapest
    1. Fly from Ft. Myers (RSW) to Tocumen International Airport (PTY)plane plane RSW - PTY
    12h
    $172–643

  3. Drive 6,041 km

    1. Drive from Cape Coral to Panama Citycar car 6,041 km
    3d 7h
    $827–1,194

  4. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Tocumen International Airport (PTY)plane plane FLL - PTY
    10h 10m
    $390–626

  5. Bus to Tampa, fly

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Tocumen International Airport (PTY)plane plane TPA - PTY
    12h 26m
    $432–684

  6. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Tocumen International Airport (PTY)plane plane SRQ - PTY
    12h 47m
    $182–664

Miami International Airport (MIA) to Tocumen International Airport (PTY) flights

Calendar55Weekly Planes
Duration3h 6mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Cape Coral to Panama City.ExpandLaunch map view
  • Distance: 2,170.3 km
  • Duration: 10h 59m

What companies run services between Cape Coral, FL, USA and Panama City, Panama?

Delta, United Airlines, and two other airlines fly from Ft. Myers (RSW) to Tocumen International Airport (PTY) 5 times a day.

Airlines
Bus operators

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