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How to get fromCartagena to Panamaby bus, plane, or train

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There are 7 ways to get from Cartagena to Panama by bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, bus to Alicante-Elche Airport, fly to Tocumen International Airport

    best
    1. Take the bus from Estación de Autobuses de Cartagena to Estación de Autobuses de Murciabus bus
    2. Take the bus from Estación de Autobuses de Murcia to Alicante Aeropuertobus bus
    3. Fly from Alicante-Elche Airport (ALC) to Tocumen International Airport (PTY)plane plane ALC - PTY
    18h 23m
    $422–1,158

  2. Bus to Almería Airport, fly to Tocumen International Airport

    1. Take the bus from Cartagena to Almeríabus bus
    2. Fly from Almería Airport (LEI) to Tocumen International Airport (PTY)plane plane LEI - PTY
    19h 53m
    $611–1,777

  3. Train, train to Valencia Airport, fly to Tocumen International Airport

    1. Take the train from Cartagena to Murcia Del Carmentrain train
    2. Take the train from Murcia Del Carmen to Alacant/Alicante Terminaltrain train
    3. Take the train from Alacant/Alicante Terminal to Estació del Nordtrain train
    4. Fly from Valencia Airport (VLC) to Tocumen International Airport (PTY)plane plane VLC - PTY
    21h 36m
    $688–1,224

  4. Train, train to Adolfo Suárez Madrid–Barajas Airport, fly to Tocumen International Airport

    1. Take the train from Cartagena to Murcia Del Carmentrain train
    2. Take the train from Murcia Del Carmen to Madrid Chamartíntrain train
    3. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Tocumen International Airport (PTY)plane plane MAD - PTY
    18h 52m
    $531–1,117

  5. Bus, bus to Federico García Lorca Granada-Jaén Airport, fly to Tocumen International Airport

    1. Take the bus from Estación de Autobuses de Cartagena to Estación de Autobuses de Murciabus bus
    2. Take the bus from Estación de Autobuses de Murcia to Granada Estación de Autobusesbus bus
    3. Fly from Federico García Lorca Granada-Jaén Airport (GRX) to Tocumen International Airport (PTY)plane plane GRX - PTY
    22h
    $512–1,490

  6. Train, train to Adolfo Suárez Madrid–Barajas Airport, fly to Panama Pacific International Airport

    1. Take the train from Cartagena to Murcia Del Carmentrain train
    2. Take the train from Murcia Del Carmen to Madrid Chamartíntrain train
    3. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Panama Pacific International Airport (BLB)plane plane MAD - BLB
    22h 31m
    $498–1,498

  7. Bus, bus to Alicante-Elche Airport, fly to David

    1. Take the bus from Estación de Autobuses de Cartagena to Estación de Autobuses de Murciabus bus
    2. Take the bus from Estación de Autobuses de Murcia to Alicante Aeropuertobus bus
    3. Fly from Alicante-Elche Airport (ALC) to David (DAV)plane plane ALC - DAV
    22h 38m
    $515–1,622

Alicante-Elche Airport (ALC) to Tocumen International Airport (PTY) flights

Calendar19Weekly Planes
Duration14h 22mAverage Duration
Ticket$354Cheapest Price
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Questions & Answers

Map of how to get from Cartagena to Panama.ExpandLaunch map view
  • Distance: 8,559.4 km
  • Duration: 18h 23m

What companies run services between Cartagena, Spain and Panama?

There is no direct connection from Cartagena to Panama. However, you can take the bus to Estación de Autobuses de Murcia, take the bus to Alicante Aeropuerto, walk to Alicante-Elche Airport (ALC) airport, fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, then take the shuttle to Las Cumbres. Alternatively, you can take the bus to Almería, walk to Estacion Intermodal-Al, take the bus to Aeropuerto Almeria-Al, walk to Almería Airport (LEI) airport, fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, then take the shuttle to Las Cumbres.

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