Rome2Rio

How to get fromCayo Santa María to Sancti Spíritusby bus, car, taxi, or train

Find Transport to Sancti Spíritus

See all options

There are 5 ways to get from Cayo Santa María to Sancti Spíritus by bus, car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Sancti Spíritusbus bus Sancti Spíritus / ...
    4h 5m
    $18–31
  2. Bus via Santa Clara

    cheapest
    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Sancti Spíritusbus bus Sancti spiritus
    5h
    $11–20
  3. Drive 137.9 km

    1. Drive from Cayo Santa María to Sancti Spírituscar car 137.9 km
    1h 57m
    $16–23
  4. Taxi

    1. Take the taxi from Cayo Santa María to Sancti Spíritustaxi taxi 137.9 km
    1h 57m
    $95–120
  5. Bus, train

    1. Take the bus from Cayo Santa María to Remediosbus bus Santa Clara
    2. Take the train from Placetas to Sancti Spiritustrain train 105 Habana
    4h 5m
    $34–43

Questions & Answers

What companies run services between Cayo Santa María, Villa Clara, Cuba and Sancti Spíritus, Cuba?

You can take a bus from Cayo Santa María to Sancti Spíritus via Santa Clara in around 4h 5m.

Train operators
Bus operators
Other operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Italian Lakes: Getting around by train, Getting to Rome from the airport, and Best ways to travel around Australia - to help you get the most out of your next trip.