How to get fromGuayaquil to Panama Cityby plane, bus, ferry, or car

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There are 3 ways to get from Guayaquil to Panama City by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY)plane GYE - PTY
3h 5m
$243–476
Bus, ferry, drive via Ipiales
1. Take the bus from Guayaquil to Terminal Terrestre Quitumbebus
2. Take the bus from Terminal Terrestre Quitumbe to Rumichacabus
3. Take the bus from Terminales de Transportes de Ipiales to Terminal Salitrebus
4. Take the bus from Terminal Salitre to Terminal de Transporte de Cartagenabus
5. Take the ferry from Cartagena to Portobeloferry
6. Drive from Portobelo to Panama Citycar
8d 14h
$863–968
Bus, ferry, drive
1. Take the bus from Terminal Terrestre de Guayaquil to Cúcutabus
2. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
3. Take the ferry from Cartagena to Portobeloferry
4. Drive from Portobelo to Panama Citycar
8d 17h
$894–1,025

José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) flights

50Weekly Planes

2h 51mAverage Duration

$67Cheapest Price

Questions & Answers

Map of how to get from Guayaquil to Panama City.

Launch map view

Distance: 1,272.7 km
Duration: 3h 5m

What companies run services between Guayaquil, Ecuador and Panama City, Panama?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) every 4 hours.

Airlines

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Ferry operators

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Panama City, Panama(opens in a new window)

Panama City, also known as Panama (or Panamá in Spanish), is the capital and largest city of Panama. It has a total population of 1,938,000, with over 1,500,000 in its urban area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for banking and commerce.

Places to stay in Panama City

Plaza Paitilla Inn(Opens in a new window)

8.9Fabulous

Ramada Plaza by Wyndham Panama Punta Pacifica(Opens in a new window)

9.2Superb

Megapolis Hotel Panama(Opens in a new window)

8.5Very Good

Global Hotel Panama(Opens in a new window)

8.6Fabulous

Rome2Rio makes travelling from Guayaquil to Panama City easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Guayaquil to Panama City right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.