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How to get fromKnoxville to Panama Cityby plane or car

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There are 4 ways to get from Knoxville to Panama City by plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Tocumen International Airport (PTY)plane plane TYS - PTY
    7h 33m
    $295–955

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Tocumen International Airport (PTY)plane plane AVL - PTY
    9h 9m
    $190–620

  3. Drive 5,756 km

    1. Drive from Knoxville to Panama Citycar car 5,756 km
    3d 4h
    $788–1,138

  4. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Tocumen International Airport (PTY)plane plane CHA - PTY
    9h 28m
    $287–1,065

Mcghee Tyson Airport (TYS) to Tocumen International Airport (PTY) flights

Calendar41Weekly Planes
Duration7h 50mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Panama City.ExpandLaunch map view
  • Distance: 3,053.8 km
  • Duration: 7h 33m

What companies run services between Knoxville, TN, USA and Panama City, Panama?

Delta, American Airlines, and four other airlines fly from Mcghee Tyson Airport (TYS) to Tocumen International Airport (PTY) every 4 hours.

Airlines

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