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How to get fromMexico City to Panama Cityby plane, bus, or car

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There are 4 ways to get from Mexico City to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Benito Juárez International Airport

    best
    1. Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane plane MEX - PTY
    6h 34m
    $268–590

  2. Bus

    cheapest
    1. Take the bus from México City to Tapachulabus bus
    2. Take the bus from Tapachula to San Salvadorbus bus
    3. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    4. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 16h
    $221–294

  3. Drive 3,155 km

    1. Drive from Mexico City to Panama Citycar car 3,155 km
    45h 9m
    $432–624

  4. Fly from Felipe Ángeles International Airport

    1. Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane plane NLU - PTY
    9h 33m
    $351–999

Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights

Calendar59Weekly Planes
Duration4h 22mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Mexico City to Panama City.ExpandLaunch map view
  • Distance: 2,441.3 km
  • Duration: 6h 34m

What companies run services between Mexico City, Mexico and Panama City, Panama?

Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) every 4 hours. Alternatively, you can take a bus from México City to Terminal Tica Bus Panamá via Tapachula, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 2d 16h.

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