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How to get fromPort Saint Lucie to Panama Cityby bus, plane, or car

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There are 6 ways to get from Port Saint Lucie to Panama City by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Miami International Airport, fly

    best
    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Tocumen International Airport (PTY)plane plane MIA - PTY
    8h 46m
    $291–532

  2. Bus to President Donald J. Trump International Airport, fly

    cheapest
    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Tocumen International Airport (PTY)plane plane PBI - PTY
    12h 1m
    $208–642

  3. Drive 6,044.2 km

    1. Drive from Port Saint Lucie to Panama Citycar car 6,044.2 km
    3d 6h
    $827–1,195

  4. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Tocumen International Airport (PTY)plane plane MCO - PTY
    9h 38m
    $372–571

  5. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Tocumen International Airport (PTY)plane plane FLL - PTY
    8h 27m
    $399–631

  6. Bus to Tampa, fly

    1. Take the bus from Port St Lucie to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Tocumen International Airport (PTY)plane plane TPA - PTY
    11h 42m
    $471–732

Miami International Airport (MIA) to Tocumen International Airport (PTY) flights

Calendar55Weekly Planes
Duration3h 6mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Panama City.ExpandLaunch map view
  • Distance: 2,074.9 km
  • Duration: 8h 46m

What companies run services between Port Saint Lucie, FL, USA and Panama City, Panama?

There is no direct connection from Port Saint Lucie to Panama City. However, you can take the bus to Sheridan Tri-Rail Station, walk to Sheridan Street Station, take the train to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the vehicle to Miami International Airport, walk to Miami International Airport (MIA) airport, fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, then take the shuttle to Amador. Alternatively, you can drive from Port Saint Lucie to Panama City in around 3d 6h.

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