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How to get fromSan Francisco to Panama Cityby plane, bus (Flixbus), car, or train

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There are 5 ways to get from San Francisco to Panama City by plane, bus (Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Tocumen International Airport (PTY)plane plane SFO - PTY
    10h 34m
    $458–650

  2. Caltrain to Norman Y. Mineta San José International Airport, fly

    cheapest
    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Tocumen International Airport (PTY)plane plane SJC - PTY
    13h 13m
    $260–852

  3. Bus

    1. Take the bus from San Francisco to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles to Managuabus bus
    3. Take the bus from Managua to Terminal NicaBusbus bus
    4. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    5d 18h
    $490–630

  4. Drive 6,676 km

    1. Drive from San Francisco to Panama Citycar car 6,676 km
    3d 11h
    $914–1,320

  5. Fly from Oakland International Airport

    1. Fly from Oakland International Airport (OAK) to Tocumen International Airport (PTY)plane plane OAK - PTY
    12h 19m
    $384–846

San Francisco International Airport (SFO) to Tocumen International Airport (PTY) flights

Calendar32Weekly Planes
Duration8h 58mAverage Duration
Ticket$185Cheapest Price
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Questions & Answers

Map of how to get from San Francisco to Panama City.ExpandLaunch map view
  • Distance: 5,391.4 km
  • Duration: 10h 34m

What companies run services between San Francisco, CA, USA and Panama City, Panama?

Copa Airlines, Avianca - Aerovías del Continente Americano S.A., and Aeroméxico fly from San Francisco International Airport (SFO) to Tocumen International Airport (PTY) 5 times a day. Alternatively, you can take a bus from San Francisco to Terminal Tica Bus Panamá via Los Angeles Union Station, Cesar E Chavez / Vignes, Los Angeles, Managua, Terminal NicaBus, and Terminal Tica Bus San José in around 5d 18h.

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Want to know more about travelling around Panama

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