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How to get fromSanta Cruz de la Sierra to Panama Cityby plane, bus, ferry, or car

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There are 3 ways to get from Santa Cruz de la Sierra to Panama City by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Viru Viru International Airport (VVI) to Tocumen International Airport (PTY)plane plane VVI - PTY
    8h 13m
    $429–739

  2. Bus, ferry, drive

    1. Take the bus from Santa Cruz to La Pazbus bus
    2. Take the bus from La Paz to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Gran Terminal Terrestre Plaza Norte to Cúcutabus bus
    4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus bus
    5. Take the ferry from Cartagena to Portobeloferry ferry
    6. Drive from Portobelo to Panama Citycar car
    10d 18h
    $1,045–1,180

  3. Bus, ferry, drive via Lima

    1. Take the bus from Santa Cruz to La Pazbus bus
    2. Take the bus from La Paz to Oltursa Lima Terminalbus bus
    3. Take the bus from Gran Terminal Terrestre Plaza Norte to Cúcutabus bus
    4. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus bus
    5. Take the ferry from Cartagena to Portobeloferry ferry
    6. Drive from Portobelo to Panama Citycar car
    10d 20h
    $1,129–1,275

Viru Viru International Airport (VVI) to Tocumen International Airport (PTY) flights

Calendar18Weekly Planes
Duration5h 28mAverage Duration
Ticket$174Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz de la Sierra to Panama City.ExpandLaunch map view
  • Distance: 3,508.2 km
  • Duration: 8h 13m

What companies run services between Santa Cruz de la Sierra, Bolivia and Panama City, Panama?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Viru Viru International Airport (VVI) to Tocumen International Airport (PTY) 3 times a day.

Airlines
Bus operators
Ferry operators

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