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How to get fromSanta Fe to Panama Cityby plane, train, bus, or car

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There are 4 ways to get from Santa Fe to Panama City by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Santa Fe Municipal Airport

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to Tocumen International Airport (PTY)plane plane SAF - PTY
    11h 43m
    $229–763

  2. Train, bus

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Take the train from Albuquerque Alvarado Transportation Center to Los Angelestrain train
    3. Take the bus from Los Angeles to Managuabus bus
    4. Take the bus from Managua to Terminal NicaBusbus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    6d 5h
    $709–1,128

  3. Drive 5,275.3 km

    1. Drive from Santa Fe to Panama Citycar car 5,275.3 km
    2d 21h
    $722–1,043

  4. Train to Albuquerque International Airport, fly

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to Tocumen International Airport (PTY)plane plane ABQ - PTY
    12h 56m
    $244–897

Santa Fe Municipal Airport (SAF) to Tocumen International Airport (PTY) flights

Calendar27Weekly Planes
Duration12h 36mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to Panama City.ExpandLaunch map view
  • Distance: 4,044.4 km
  • Duration: 11h 43m

What companies run services between Santa Fe, NM, USA and Panama City, Panama?

United Airlines, Copa Airlines, and American Airlines fly from Santa Fe Municipal Airport (SAF) to Tocumen International Airport (PTY) 4 times a day.

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