There are 9 ways to get from Santiago to Panama City by bus, car, taxi, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Penonomé
best- Take the bus from Santiago de Veraguas to Penonomébus Panamá
- Take the bus from Penonomé to Panama Albrookbus
3h 43m$19–27Bus #2
cheapest- Take the bus from Santiago to Albrookbus Panama City
4h 4m$6–24Drive 252.1 km
- Drive from Santiago to Panama Citycar 252.1 km
3h 46m$35–50Taxi
- Take the taxi from Santiago to Panama Citytaxi 252.1 km
3h 46m$140–170Taxi to Lago Bay, fly to Albrook Airport
- Take the taxi from Santiago to Lago Baytaxi
- Fly from Lago Bay to Albrook Airportplane
2h 24m$856–2,266Shuttle
- Take a shuttle bus from Santiago to Panama City
4h 11m$300Bus
- Take the bus from Santiago to Panama Citybus David
3h 52m$10–18Bus #3
- Take the bus from Santiago to Capirabus Santiago
- Take the bus from Capira to Albrookbus Santiago
5h 25mBus, bus to Chitre, fly to Albrook Marcos A. Gelabert International Airport
- Take the bus from Santiago to Ocubus
- Take the bus from Ocu to Chitrébus
- Fly from Chitre (CTD) to Albrook Marcos A. Gelabert International Airport (PAC)plane CTD - PAC
4h 5m$147–154
Santiago to Panama City by bus
Questions & Answers
The cheapest way to get from Santiago to Panama City is to bus which costs $10 - $18 and takes 3h 52m.
The fastest way to get from Santiago to Panama City is to taxi and fly which takes 2h 24m and costs $850 - $2,300.
Yes, there is a direct bus departing from Santiago and arriving at Albrook. Services depart twice daily, and operate every day. The journey takes approximately 4h 4m.
The distance between Santiago and Panama City is 258 km. The road distance is 252.1 km.
The best way to get from Santiago to Panama City without a car is to bus via Penonomé which takes 3h 43m and costs $19 - $28.
It takes approximately 3h 43m to get from Santiago to Panama City, including transfers.
Santiago to Panama City bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), depart from Santiago de Veraguas station.
Santiago to Panama City bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), arrive at Penonomé station.
Yes, the driving distance between Santiago to Panama City is 252 km. It takes approximately 3h 46m to drive from Santiago to Panama City.
There are 887+ hotels available in Panama City.
What companies run services between Santiago, Panama and Panama City, Panama?
You can take a bus from Santiago de Veraguas to Fernandez de Cordoba via Penonomé, Panama Albrook, and Albrook in around 3h 43m.
- Website
- airpanama.com
Flights from Chitre to Albrook Marcos A. Gelabert International Airport
- Ave. Duration
- 30 min
- When
- Tuesday to Friday
- Estimated price
- $30–250
Bus from Santiago de Veraguas to Penonomé
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–11
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $7–11
Bus from Penonomé to Panama Albrook
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $11–16
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $11–16
- Phone
- +507 303-6466
Bus from Penonomé to Panama Albrook
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $6
- Phone
- +507 6687 1802
- [email protected]
- Website
- Valitours Transportation
Shuttle from Santiago to Panama City
- Ave. Duration
- 4h 11m
- Frequency
- On demand
- Estimated price
- $300
- Website
- Valitours Transportation
Bus from Santiago to Panama City
- Ave. Duration
- 3h 42m
- Frequency
- Hourly
- Estimated price
- $17
Bus from Santiago to Panama City
- Ave. Duration
- 4h
- Frequency
- Every 2 hours
- Estimated price
- $13
- Schedules at
- Transporte Panama Chiriqui Frontera S.A (Panachif)
- Phone
- +507958-6484
- Website
- Expreso Veraguense
Bus from Santiago to Panama City
- Ave. Duration
- 4h 30m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- Expreso Veraguense
Bus from Santiago to Capira
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- Expreso Veraguense
Bus from Capira to Albrook
- Ave. Duration
- 1h
- Frequency
- Hourly
- Schedules at
- Expreso Veraguense
- Phone
- +507 314 6231
- Website
- Vepasa Sanpasa
Bus from Santiago to Panama City
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $11
- Website
- Vepasa Sanpasa
- Phone
- +507 775-2974
- [email protected]
- Website
- Terminales Panama David
Bus from Santiago to Albrook
- Ave. Duration
- 4h 4m
- Frequency
- Hourly
- Estimated price
- $13
- Schedules at
- Terminales Panama David
- Phone
- +507 303 6326
- [email protected]
- Website
- Tranceibosa Bocas del Toro
Bus from Santiago to Albrook
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $6–24
- Schedules at
- Tranceibosa Bocas del Toro
- Child
- $6–8
- Adult
- $12–15
Bus from Santiago to Ocu
- Ave. Duration
- 1h
- Frequency
- Every 20 minutes
- Estimated price
- $2
Bus from Ocu to Chitré
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Ave. Duration
- 2h 43m
- Estimated price
- $55–170
Cooperativa de Transporte Joaquina H De Torrijos, R. L.
- Phone
- +507 958-7240
- Website
- cootrajoht.com
Radio Taxi Sicotive
- Phone
- +507 998-2611
Selectivo Santiago Sesasa
- Phone
- +507 958-5933
Cooperativa de Transporte Joaquina H De Torrijos, R. L.
- Phone
- +507 958-7240
- Website
- cootrajoht.com
Radio Taxi Sicotive
- Phone
- +507 998-2611
Selectivo Santiago Sesasa
- Phone
- +507 958-5933
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