There are 3 ways to get from Santiago to Panama City by plane, bus, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Tocumen International Airport
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY)plane SCL - PTY
10h 7m$340–640Fly to Panama Pacific International Airport
cheapest- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Panama Pacific International Airport (BLB)plane SCL - BLB
12h 28m$259–723Bus, ferry, drive
- Take the bus from Terminal San Borja to Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
10d 14h$1,191–1,304
Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from Santiago to Panama City is to fly which costs $250 - $750 and takes 12h 28m.
The fastest way to get from Santiago to Panama City is to fly which takes 10h 7m and costs $340 - $650.
The distance between Santiago and Panama City is 4847 km.
It takes approximately 10h 7m to get from Santiago to Panama City, including transfers.
Panama City is 1h behind Santiago. It is currently 11:49 AM in Santiago and 10:49 AM in Panama City.
There are 889+ hotels available in Panama City.
What companies run services between Santiago, Chile and Panama City, Panama?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY) every 3 hours.
- Website
- copaair.com
Flights from Comodoro Arturo Merino Benítez International Airport to Tocumen International Airport
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $150–600
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 9h 58m
- When
- Every day
- Estimated price
- $300–600
- Website
- copaair.com
Flights from Comodoro Arturo Merino Benítez International Airport to Panama Pacific International Airport via Bogota
- Ave. Duration
- 9h 54m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $250–800
Flights from Comodoro Arturo Merino Benítez International Airport to Panama Pacific International Airport via Cartagena
- Ave. Duration
- 10h 28m
- When
- Sunday
- Estimated price
- $300–950
Flights from Comodoro Arturo Merino Benítez International Airport to Panama Pacific International Airport via Medellin Jose Marie Cordova
- Ave. Duration
- 17h 15m
- When
- Tuesday and Friday
- Estimated price
- $240–700
Flights from Comodoro Arturo Merino Benítez International Airport to Panama Pacific International Airport via Guayaquil, Quito
- Ave. Duration
- 11h 45m
- When
- Thursday and Sunday
- Estimated price
- $250–800
Flights from Comodoro Arturo Merino Benítez International Airport to Panama Pacific International Airport via Lima, Quito
- Ave. Duration
- 17h 45m
- When
- Wednesday and Saturday
- Estimated price
- $250–800
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- facebook.com
Bus from Terminal San Borja to Cúcuta
- Ave. Duration
- 3d 17h
- Frequency
- Once daily
- Estimated price
- $420–500
- Website
- https://www.facebook.com/lineasdelosandesve/
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $45–70
- Phone
- 01 800 051 8001
- [email protected]
- Website
- expresobrasilia.com
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- $40–66
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $40–60
- Phone
- +57 310 704 0425
- [email protected]
- Website
- bluesailing.net
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- https://bluesailing.net/en_us/
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Which London airport should I choose?, Travelling by boat in Italy, and South Korea: Travelling from Seoul to Busan - to help you get the most out of your next trip.










