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How to get fromSt. Louis Airport (STL) to Panama Cityby plane, bus (Greyhound, Flixbus), or car

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There are 4 ways to get from St. Louis Airport (STL) to Panama City by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tocumen International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY)plane plane STL - PTY
    7h 43m
    $263–751

  2. Bus

    1. Take the bus from Saint Louis to Oklahoma City Bus Stationbus bus
    2. Take the bus from Oklahoma City Bus Station to Downtown Houstonbus bus
    3. Take the bus from Houston to San Salvadorbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    5d 12h
    $458–849

  3. Drive 5,583.7 km

    1. Drive from St-Louis-Airport-STL to Panama Citycar car 5,583.7 km
    3d
    $764–1,104

  4. Fly to Panama Pacific International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Panama Pacific International Airport (BLB)plane plane STL - BLB
    17h 4m
    $265–707

Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) flights

Calendar35Weekly Planes
Duration7h 8mAverage Duration
Ticket$202Cheapest Price
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Questions & Answers

Map of how to get from St. Louis Airport (STL) to Panama City.ExpandLaunch map view
  • Distance: 3,501.1 km
  • Duration: 7h 43m

What companies run services between St. Louis Airport (STL), USA and Panama City, Panama?

Delta, American Airlines, and three other airlines fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) 5 times a day. Alternatively, you can take a bus from Saint Louis to Terminal Tica Bus Panamá via Oklahoma City Bus Station, Downtown Houston, Wheeler Station, Houston, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 5d 12h.

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